Reprogramming committed B lineage cells

Cornelis Murre

doi:10.1016/j.cell.2004.05.006

Reprogramming committed B lineage cells

Cell. 2004 May 28;117(5):556-8. doi: 10.1016/j.cell.2004.05.006.

Author

Cornelis Murre¹

Affiliation

¹ Divison of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.

PMID: 15163403
DOI: 10.1016/j.cell.2004.05.006

Abstract

It is generally assumed that once a cell commits to a certain lineage it no longer can change its fate. A new study in this issue of Cell provides compelling evidence that committed mature B lineage cells can be reprogrammed to become macrophages.

Publication types

Comment

MeSH terms

Animals
B-Lymphocytes / physiology*
CCAAT-Enhancer-Binding Proteins / physiology
Cell Differentiation / genetics
Cell Differentiation / physiology*
Gene Expression Regulation / physiology
Hodgkin Disease / etiology
Humans
Macrophages / physiology

Substances

CCAAT-Enhancer-Binding Proteins