Syndecans and HIV-1 pathogenesis

Microbes Infect. 2004 May;6(6):617-22. doi: 10.1016/j.micinf.2004.02.004.

Abstract

The exploitation of receptors represents a common microbial strategy to survive in the hostile environment of the host. A growing body of evidence suggests that HIV-1 exploits a specific class of receptors-the syndecans-to facilitate colonization of the host.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • HIV Infections / virology*
  • HIV-1 / metabolism
  • HIV-1 / pathogenicity*
  • Heparitin Sulfate / metabolism
  • Humans
  • Macrophages / virology
  • Membrane Glycoproteins / metabolism*
  • Proteoglycans / metabolism*
  • Receptors, HIV / metabolism
  • Syndecans
  • T-Lymphocytes / virology
  • Virus Replication

Substances

  • Membrane Glycoproteins
  • Proteoglycans
  • Receptors, HIV
  • Syndecans
  • Heparitin Sulfate