Isolated metastases to the pancreas are rare. Renal cell carcinoma is one of the few tumours that metastasis to the pancreas. Since 2001 we have observed two cases of isolated metastases to the pancreas from renal cell carcinomas, both of which were surgically resected with a diagnostic and therapeutic intent. The aim of this report was to examine the clinical manifestations and radiological appearances of these metastases through the presentation of our two cases and a review of the literature, in addition to assessing the respective roles of FNAB in the diagnostic phase and of surgery in the therapeutic phase.