Iak antigen and interleukin-1 secretion by lymphocytes and monocytes of mice fed a lipid-rich diet

J Med. 1992;23(2):127-32.

Abstract

Female mice were maintained on a lipid-rich diet. After 33 days, the mice showed a decrease in the cell population bearing MHC class II molecules, and in the production of interleukin-1 (IL-1). After 60 days, we reported a further decrease of the cell population with MHC class II molecules and the secretion IL-1.

MeSH terms

  • Animals
  • Dietary Fats / administration & dosage*
  • Female
  • Histocompatibility Antigens Class II / analysis*
  • Interleukin-1 / biosynthesis*
  • Lymphocyte Activation
  • Lymphocytes / immunology
  • Lymphocytes / metabolism*
  • Mice
  • Mice, Inbred C3H
  • Monocytes / immunology
  • Monocytes / metabolism*

Substances

  • Dietary Fats
  • Histocompatibility Antigens Class II
  • Interleukin-1