Application of comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry in the analysis of volatile oil of traditional Chinese medicines

Jianfang Wu; Xin Lu; Wanying Tang; Hongwei Kong; Shenfan Zhou; Guowang Xu

doi:10.1016/j.chroma.2004.02.028

Application of comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry in the analysis of volatile oil of traditional Chinese medicines

J Chromatogr A. 2004 Apr 23;1034(1-2):199-205. doi: 10.1016/j.chroma.2004.02.028.

Authors

Jianfang Wu¹, Xin Lu, Wanying Tang, Hongwei Kong, Shenfan Zhou, Guowang Xu

Affiliation

¹ National Chromatographic R&A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116011, China.

PMID: 15116931
DOI: 10.1016/j.chroma.2004.02.028

Abstract

This paper reports comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GC x GC-TOF MS) analysis of Pogostemon cablin Benth (Cablin Parchouli) volatile oil. The suitable column system and operation conditions were chosen on the basis of the properties of composition of the volatile oil. One-dimensional gas chromatography (ID-GC) and GC x GC, GC-MS and GC x GC-TOF MS were compared under appropriate conditions, and the enhanced sensitivity and superior resolution of GC x GC were demonstrated. 394 components were tentatively identified by GC x GC-TOF MS.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Gas Chromatography-Mass Spectrometry / methods*
Medicine, Chinese Traditional*
Oils, Volatile / analysis*
Sensitivity and Specificity
Volatilization

Substances

Oils, Volatile