This report presents results of studies of the phenomenon of mismatch negativity (MMN) during exposure to four blocks of sound stimuli each containing identical standards creating an immobile sound image located along the midline of the head and one of a set of deviants, creating a sound image located either by the left ear or moving from the midline of the head towards the left ear or in the opposite direction. All deviants induced mismatch negativity; the minimal amplitude and longest latent period were seen in the mismatch negativity produced by the deviant modeling movement of the sound image from the midline of the head to the left ear. The question of the appearance of mismatch negativity as a criterion for the accurate discrimination of signals with different localizing characteristics is discussed.