Panton-valentine leukocidin and staphyloccoccal skin infections in schoolchildren

Emerg Infect Dis. 2004 Jan;10(1):121-4. doi: 10.3201/eid1001.030144.

Abstract

The Panton-Valentine leukocidin is associated with staphylococcal skin and pulmonary infections. We describe a school outbreak of skin infections and the public health response to it. Nasal carriage of a Panton-Valentine leukocidin-positive Staphylococcus aureus clone was detected only in previously ill classmates and their family members.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Toxins
  • Carrier State
  • Child
  • Chlorhexidine / therapeutic use
  • Disease Outbreaks*
  • Electrophoresis, Gel, Pulsed-Field
  • Exotoxins
  • Humans
  • Leukocidins / isolation & purification*
  • Mupirocin / therapeutic use
  • Nasal Mucosa / microbiology
  • Polymerase Chain Reaction
  • Skin Diseases / epidemiology*
  • Skin Diseases / microbiology
  • Skin Diseases / prevention & control
  • Staphylococcus aureus / genetics*
  • Staphylococcus aureus / isolation & purification
  • Switzerland / epidemiology

Substances

  • Anti-Bacterial Agents
  • Bacterial Toxins
  • Exotoxins
  • Leukocidins
  • Panton-Valentine leukocidin
  • Mupirocin
  • Chlorhexidine