Kaposi varicelliform eruption associated with 0.1% tacrolimus ointment treatment in atopic blepharitis

Cornea. 2004 Mar;23(2):190-3. doi: 10.1097/00003226-200403000-00013.

Abstract

Objective: To report the association of Kaposi varicelliform eruption (KVE) with 0.1% tacrolimus ointment treatment of atopic blepharitis in a patient with atopic dermatitis (AD).

Method: We encountered KVE in a 20-year-old male patient with atopic blepharitis and AD who developed generalized herpetic lesions on his face 28 days after commencement of treatment.

Result: The lesions resolved quickly with intravenous acyclovir treatment.

Conclusion: Ophthalmologists should be well aware of KVE as a complication of immunosuppressive treatment in patients with atopic blepharitis.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / therapeutic use
  • Adult
  • Antiviral Agents / therapeutic use
  • Blepharitis / drug therapy*
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Kaposi Varicelliform Eruption / chemically induced*
  • Kaposi Varicelliform Eruption / drug therapy
  • Male
  • Ointments
  • Tacrolimus / adverse effects*
  • Virus Activation / drug effects

Substances

  • Antiviral Agents
  • Immunosuppressive Agents
  • Ointments
  • Tacrolimus
  • Acyclovir