Abstract
Invasive bacteria actively induce their own uptake by phagocytosis in normally nonphagocytic cells and then either establish a protected niche within which they survive and replicate, or disseminate from cell to cell by means of an actin-based motility process. The mechanisms underlying bacterial entry, phagosome maturation, and dissemination reveal common strategies as well as unique tactics evolved by individual species to establish infection.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Actins / physiology
-
Animals
-
Bacteria / growth & development
-
Bacteria / pathogenicity*
-
Bacterial Adhesion
-
Bacterial Physiological Phenomena*
-
Bacterial Proteins / metabolism
-
Cytosol / microbiology
-
Enterobacteriaceae / pathogenicity*
-
Enterobacteriaceae / physiology
-
Epithelial Cells / microbiology*
-
Epithelial Cells / physiology
-
Humans
-
Intestinal Mucosa / microbiology*
-
Intestinal Mucosa / physiology
-
Listeria monocytogenes / pathogenicity*
-
Listeria monocytogenes / physiology
-
Mice
-
Models, Biological
-
Movement
-
Phagocytosis
-
Phagosomes / microbiology
-
Phagosomes / physiology
-
Vacuoles / microbiology
Substances
-
Actins
-
Bacterial Proteins