3-[4-(4-fluorophenyl)piperazin-1-ylmethyl]-5-methyl-1,3-benzoxazol-2(3H)-one and 3-[4-(2-fluorophenyl)piperazin-1-ylmethyl]-5-methyl-1,3-benzoxazol-2(3H)-one

Acta Crystallogr C. 2004 Apr;60(Pt 4):o232-4. doi: 10.1107/S0108270104003269. Epub 2004 Mar 11.

Abstract

The title compounds, both C(19)H(20)FN(3)O(2), contain essentially planar benzoxazolinone ring systems, within which the C-N bond distances and angles do not differ significantly between the two compounds. In both cases, the piperazine ring adopts an almost perfect chair conformation and the benzoxazolinone ring system lies nearly perpendicular to it. The structures contain intermolecular C-H.O contacts, and the interactions between the benzoxazolinone and fluorophenylpiperazine portions of the molecules are segregated.