Electrochemical sensing with electrodes modified with molecularly imprinted polymer films

Anal Bioanal Chem. 2004 Apr;378(8):1922-8. doi: 10.1007/s00216-003-2330-2. Epub 2003 Dec 20.

Abstract

This article summarises our work on the development of voltammetric sensors based on molecularly imprinted polymers. Several recognition elements and integration strategies were used:1.membranes electropolymerised at the electrode surface; 2.casting of polymeric membranes by drop-coating a solution of pre-formed polymer (polyphosphazene) and template in a low-boiling-point solvent on to the electrode surface; 3.preparation of composite membranes containing conductive material (graphite or carbon black), acrylic-type molecularly imprinted polymers (small particle size), and PVC as binder; and 4.in-situ polymerisation of a thin layer of acrylic imprinted polymer deposited on the electrode surface by spin coating. All the options evaluated offer the possibility of controlling electrode characteristics such as hydrophobic/hydrophilic character, permeability, or film thickness, which are essential for obtaining good sensor performance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chemistry Techniques, Analytical / instrumentation*
  • Chemistry Techniques, Analytical / methods*
  • Electrochemistry
  • Electrodes
  • Molecular Structure
  • Organophosphorus Compounds / chemistry
  • Plastics / chemical synthesis
  • Plastics / chemistry
  • Polymers / chemical synthesis*
  • Polymers / chemistry*

Substances

  • Organophosphorus Compounds
  • Plastics
  • Polymers
  • poly(phosphazene)