Phase-locked alpha and theta oscillations generate the P1-N1 complex and are related to memory performance

Brain Res Cogn Brain Res. 2004 May;19(3):302-16. doi: 10.1016/j.cogbrainres.2003.11.016.

Abstract

An oscillatory phase resetting model is presented and data are reported which indicate that early components of the event-related potential are due to the superposition of evoked oscillations. The following hypotheses were tested and could be confirmed: (i) theta and alpha show a significant increase in phase locking during the time window of the P1 and N1 as compared to a prestimulus reference, (ii) the dynamics of event-related changes in evoked theta and alpha power obey the same principles as are known from event-related de-/synchronization research, and (iii) latency measures of the P1-N1 complex are negatively correlated with individual alpha frequency. In addition, we have found that theta phase locking is larger during encoding than recognition and that good memory performers show a larger increase in theta and alpha phase locking during recognition in the time window of the N1. Our general conclusion is that the P1-N1 complex is generated primarily by evoked alpha and theta oscillations reflecting the synchronous activation of a working- and semantic memory system.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alpha Rhythm / methods*
  • Analysis of Variance
  • Female
  • Humans
  • Male
  • Memory / physiology*
  • Photic Stimulation / methods
  • Psychomotor Performance / physiology*
  • Reaction Time / physiology
  • Theta Rhythm / methods*