Abstract
Macrophages and neutrophils are the professional phagocytes of the innate immune system. Once in the inflammatory joint or the vasculitic lesion, macrophages and neutrophils contribute to the pathology observed. This article examines the mechanisms by which phagocytes contribute to the pathogenesis of these diseases.
MeSH terms
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Animals
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Arthritis, Rheumatoid / immunology*
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Arthritis, Rheumatoid / pathology
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Granulomatosis with Polyangiitis / immunology*
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Granulomatosis with Polyangiitis / pathology
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Humans
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Macrophages / immunology
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Macrophages / pathology
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Neutrophils / immunology
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Neutrophils / pathology
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Phagocytes / immunology*
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Phagocytes / pathology
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Synovitis / immunology*
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Synovitis / pathology
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Vasculitis / immunology*
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Vasculitis / pathology