Characterization of the first VanB vancomycin-resistant Enterococcus faecium isolated in a Spanish hospital

Curr Microbiol. 2004 Mar;48(3):199-203. doi: 10.1007/s00284-003-4125-2.

Abstract

We report the detection and characterization of the first vancomycin-resistant VanB-type Enterococcus faecium to be isolated in a Spanish hospital. Sequence analysis of the vanB gene showed that this isolate belonged to subtype vanB2. Moreover, PCR amplification analysis indicated that the vanB gene cluster was linked to a Tn5382-like transposon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anti-Bacterial Agents / pharmacology
  • Base Sequence
  • DNA Transposable Elements / genetics
  • DNA Transposable Elements / physiology
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / isolation & purification
  • Drug Resistance, Bacterial
  • Enterococcus faecium / drug effects*
  • Enterococcus faecium / genetics*
  • Enterococcus faecium / growth & development
  • Enterococcus faecium / isolation & purification
  • Genes, Bacterial / genetics
  • Genes, Bacterial / physiology
  • Gram-Positive Bacterial Infections / microbiology*
  • Hospitals
  • Humans
  • Male
  • Molecular Sequence Data
  • Pressure Ulcer / microbiology
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Sequence Homology
  • Spain
  • Vancomycin / pharmacology*
  • Vancomycin Resistance*

Substances

  • Anti-Bacterial Agents
  • DNA Transposable Elements
  • DNA, Bacterial
  • Vancomycin

Associated data

  • GENBANK/AY145441