Molecular characterization of the gene encoding a new AmpC beta-lactamase in a clinical strain of acinetobacter genomic species 3

Antimicrob Agents Chemother. 2004 Apr;48(4):1374-8. doi: 10.1128/AAC.48.4.1374-1378.2004.

Abstract

A presumptive chromosomal cephalosporinase (pI, 9.0) from a clinical strain of Acinetobacter genomic species 3 (AG3) is reported. The nucleotide sequence of this beta-lactamase shows for the first time the gene encoding an AmpC enzyme in AG3. In addition, the biochemical properties of the novel AG3 AmpC beta-lactamase are reported

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter / genetics*
  • Amino Acid Sequence
  • Bacterial Proteins*
  • Base Sequence
  • Chromosomes, Bacterial / genetics
  • DNA, Bacterial / genetics
  • Genes, Bacterial / genetics*
  • Isoelectric Focusing
  • Kinetics
  • Molecular Sequence Data
  • beta-Lactamases / genetics*
  • beta-Lactamases / metabolism

Substances

  • Bacterial Proteins
  • DNA, Bacterial
  • AmpC beta-lactamases
  • beta-Lactamases