Magnetic resonance microscopy of biofilm structure and impact on transport in a capillary bioreactor

Joseph D Seymour; Sarah L Codd; Erica L Gjersing; Philip S Stewart

doi:10.1016/j.jmr.2004.01.009

Magnetic resonance microscopy of biofilm structure and impact on transport in a capillary bioreactor

J Magn Reson. 2004 Apr;167(2):322-7. doi: 10.1016/j.jmr.2004.01.009.

Authors

Joseph D Seymour¹, Sarah L Codd, Erica L Gjersing, Philip S Stewart

Affiliation

¹ Department of Chemical and Biological Engineering and Center for Biofilm Engineering, Montana State University, Bozeman, MT, USA. jseymour@coe.montana.edu

PMID: 15040989
DOI: 10.1016/j.jmr.2004.01.009

Abstract

Microorganisms that colonize surfaces, biofilms, are of significant importance due to their role in medical infections, subsurface contaminant remediation, and industrial processing. Spatially resolved data on the distribution of biomass within a capillary bioreactor, the heterogeneity of the biofilm itself and the impact on transport dynamics for a Staphylococcus epidermidis biofilm in the natural growth state are presented. The data demonstrate the ability of magnetic resonance microscopy to study spatially resolved processes in bacterial biofilms, thus providing a basis for future studies of spatially resolved metabolism and in vivo clinical detection.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Validation Study

MeSH terms

Biofilms / growth & development*
Biological Transport, Active / physiology
Bioreactors / microbiology*
Capillary Action
Image Enhancement / methods*
Magnetic Resonance Imaging / methods*
Magnetic Resonance Spectroscopy / methods*
Microscopy / methods
Rheology / methods*
Staphylococcus epidermidis / cytology*
Staphylococcus epidermidis / physiology*
Water / metabolism*

Substances

Water