Hypoxia and ischemia induce nuclear condensation and caspase activation in cardiomyocytes

Ann N Y Acad Sci. 2003 Dec:1010:728-32. doi: 10.1196/annals.1299.131.

Authors

Martin E O'Mahoney¹, Susan Logue, Eva Szegezdi, Catherine Stenson-Cox, Una Fitzgerald, Afshin Samali

Affiliation

¹ Cell Stress and Apoptosis Research Group, Department of Biochemistry, National Centre for Biomedical Engineering Science, National University of Ireland, Galway, Ireland.

PMID: 15033818
DOI: 10.1196/annals.1299.131

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Apoptosis / physiology*
Caspase 3
Caspase 8
Caspase 9
Caspases / metabolism*
Cell Hypoxia
Cell Line
Enzyme Activation
Heart / embryology
Kinetics
Muscle Cells / cytology
Muscle Cells / enzymology
Muscle Cells / physiology*
Myocardial Ischemia / pathology
Myocardial Ischemia / physiopathology*
Myocardium / cytology
Myocardium / pathology
Rats

Substances

Casp3 protein, rat
Casp8 protein, rat
Casp9 protein, rat
Caspase 3
Caspase 8
Caspase 9
Caspases