Cherubism is a benign, hereditary, autosomal dominant disease, with variable penetrance and expressivity. It presents as a characteristic indolent deformity of the lower half of the face, associated with multicystic bone tumors. The definitive diagnosis is established by pathology. Radiology contributes greatly to its diagnosis (CT or MRI scan), and preoperative arterial embolization can provide valuable help to the surgeon when excision of this hemorrhagic lesion is necessary. The present article presents a case showing the advantage of this type of devascularization prior to surgery, not previously described in the literature.