[Studies on the new triterpenoid saponin of the aerial part of Cimicifuga foetida]

Zhongguo Zhong Yao Za Zhi. 2003 Mar;28(3):230-2.
[Article in Chinese]

Abstract

Objective: To find new active constituents from the aerial part of Cimicifuga foetida.

Method: Various column chromatographic techniques were used for the isolation and purification of the principles. The structures were elucidated on the basis of spectral data and chemical evidences.

Result: Four 9,19-cycloartane triterpenoid saponins were obtained and identified as Cimifoetiside III (25-anhydrocimigenol-3-O-beta-D-galactopyranoside, 1), 25-O-acetyl-cimigenol xylopyranoside (2), 25-O-acetyl-cimigenol galactopyranoside (3), 7 beta-hydrocimigenol xylopyranoside (4).

Conclusion: Compound 1 is new and compound 4 was isolated from this plant for the first time.

Publication types

  • English Abstract

MeSH terms

  • Cimicifuga / chemistry*
  • Galactosides / chemistry
  • Galactosides / isolation & purification*
  • Lanosterol / analogs & derivatives
  • Lanosterol / chemistry
  • Lanosterol / isolation & purification*
  • Molecular Structure
  • Plant Components, Aerial / chemistry
  • Plants, Medicinal / chemistry*
  • Saponins / chemistry
  • Saponins / isolation & purification
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification

Substances

  • 7 beta-hydrocimigenol xylopyranoside
  • Galactosides
  • Saponins
  • Triterpenes
  • cimifoetiside III
  • Lanosterol