Implementation of multichannel sensors for remote biomedical measurements in a microsystems format

IEEE Trans Biomed Eng. 2004 Mar;51(3):525-35. doi: 10.1109/TBME.2003.820370.

Abstract

A novel microelectronic "pill" has been developed for in situ studies of the gastro-intestinal tract, combining microsensors and integrated circuits with system-level integration technology. The measurement parameters include real-time remote recording of temperature, pH, conductivity, and dissolved oxygen. The unit comprises an outer biocompatible capsule encasing four microsensors, a control chip, a discrete component radio transmitter, and two silver oxide cells (the latter providing an operating time of 40 h at the rated power consumption of 12.1 mW). The sensors were fabricated on two separate silicon chips located at the front end of the capsule. The robust nature of the pill makes it adaptable for use in a variety of environments related to biomedical and industrial applications.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Biomedical Engineering / instrumentation
  • Biomedical Engineering / methods
  • Biosensing Techniques / instrumentation*
  • Biosensing Techniques / methods
  • Coated Materials, Biocompatible
  • Diagnosis, Computer-Assisted / instrumentation
  • Diagnosis, Computer-Assisted / methods
  • Electrodes, Implanted
  • Electronics, Medical / instrumentation*
  • Electronics, Medical / methods
  • Equipment Design
  • Equipment Failure Analysis*
  • Hydrogen-Ion Concentration
  • Miniaturization / methods*
  • Monitoring, Ambulatory / instrumentation*
  • Monitoring, Ambulatory / methods*
  • Oxygen / analysis
  • Prostheses and Implants
  • Systems Integration
  • Telemetry / instrumentation*
  • Telemetry / methods
  • Thermography / instrumentation
  • Thermography / methods
  • Transducers*

Substances

  • Coated Materials, Biocompatible
  • Oxygen