Estimation of the proton affinity values of fifteen matrix-assisted laser desorption/ionization matrices under electrospray ionization conditions using the kinetic method

Shama Parveen Mirza; N Prasada Raju; M Vairamani

doi:10.1016/j.jasms.2003.12.001

Estimation of the proton affinity values of fifteen matrix-assisted laser desorption/ionization matrices under electrospray ionization conditions using the kinetic method

J Am Soc Mass Spectrom. 2004 Mar;15(3):431-5. doi: 10.1016/j.jasms.2003.12.001.

Authors

Shama Parveen Mirza¹, N Prasada Raju, M Vairamani

Affiliation

¹ National Center for Mass Spectrometry, Indian Institute of Chemical Technology, Hyderabad, India.

PMID: 14998547
DOI: 10.1016/j.jasms.2003.12.001

Abstract

The kinetic method, which is known to be simple, fast and precise, is used for the measurement of proton affinity values of fifteen selected matrix-assisted laser desorption/ionization matrices under electrospray ionization conditions. The stabilization of [M - H](-)/[M + Matrix - H](-) ions for beta-cyclodextrin in negative ion mode has been rationalized based on the proton affinity values of the matrices.