New trifluoromethanesulfonanilide compounds having high miticidal activity against house dust mites

Biosci Biotechnol Biochem. 2004 Feb;68(2):425-7. doi: 10.1271/bbb.68.425.

Abstract

Several 2-alkoxycarbonyltrifluoromethanesulfonanilides were prepared to examine their miticidal activity. 4-Halo-2-alkoxycarbonyltrifluoromethanesulfonanilides in particular showed good miticidal activity against Tyrophagus putrescentiae (Tp), Dermatophagoides farinae (Dp) and Chelacaropsis moorei (Cm). Amidoflumet (methyl 5-chloro-2-[(trifluoromethyl)sulfonyl]aminobenzoate) was selected and has been developed as a new miticide for house dust mites.

MeSH terms

  • Animals
  • Indicators and Reagents
  • Insecticides / chemical synthesis*
  • Insecticides / pharmacology*
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Mites / physiology*
  • Structure-Activity Relationship
  • Sulfonamides / chemical synthesis*
  • Sulfonamides / pharmacology*
  • ortho-Aminobenzoates / chemical synthesis*
  • ortho-Aminobenzoates / pharmacology*

Substances

  • Indicators and Reagents
  • Insecticides
  • Sulfonamides
  • ortho-Aminobenzoates