Immunostimulating effects of sugar cane extract on X-ray radiation induced immunosuppression in the chicken

Int Immunopharmacol. 2004 Jan;4(1):71-7. doi: 10.1016/j.intimp.2003.10.006.

Abstract

The present study was undertaken to evaluate the effect of sugar cane (Saccharum officinarum L.) extract (SCE) on the immune system of X-ray immunosuppressed chickens. SCE (500 mg/kg/day) was administrated into the crop of 3-week-old chickens for three consecutive days before or after irradiation. The results indicated that administration of SCE before or after whole body X-ray irradiation enhanced both primary and secondary immune responses in chickens immunized with sheep red blood cells and Brucella abortus (BA) as well as cell-mediated immunity measured by delayed type hypersensitivity to human gamma-globulin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adjuvants, Immunologic / pharmacology*
  • Adjuvants, Immunologic / therapeutic use
  • Animals
  • Brucella abortus / immunology
  • Bursa of Fabricius / pathology
  • Bursa of Fabricius / radiation effects
  • Chickens
  • Hypersensitivity, Delayed / immunology
  • Immune Tolerance / drug effects*
  • Immune Tolerance / radiation effects
  • Organ Size / drug effects
  • Phytotherapy
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Radiation Injuries, Experimental / drug therapy*
  • Radiation Injuries, Experimental / immunology
  • Saccharum*
  • Spleen / pathology
  • Spleen / radiation effects
  • Thymus Gland / pathology
  • Thymus Gland / radiation effects
  • Whole-Body Irradiation
  • X-Rays
  • gamma-Globulins / immunology

Substances

  • Adjuvants, Immunologic
  • Plant Extracts
  • gamma-Globulins