Abstract
A new flavonoid, dihydroglychalcone-A, was isolated from the leaves extract of Glycosmis chlorosperma in addition to two known sulphur-containing amides, dambullin and gerambullin. The structure of the new compound was assigned as 2'-hydroxy-4,6'-dimethoxy-3',4'-(2",2"-dimethylpyrano)dihydrochalcone. The extract of the leaves was also found to exhibit antimicrobial and cytotoxic activities.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chalcones
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Flavonoids / chemistry*
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Flavonoids / isolation & purification
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Flavonoids / pharmacology
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Humans
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Leukemia-Lymphoma, Adult T-Cell / pathology
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Microbial Sensitivity Tests
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Plant Extracts / chemistry
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Plant Leaves / chemistry
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Rutaceae / chemistry*
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Tumor Cells, Cultured
Substances
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2'-hydroxy-4,6'-dimethoxy-3',4'-(2'',2''-dimethylpyrano)dihydrochalcone
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Chalcones
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Flavonoids
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Plant Extracts
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dambulin
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gerambulin