A new flavonoid and sulphur-containing amides from Glycosmis chlorosperma

Nat Prod Res. 2004 Feb;18(1):85-8. doi: 10.1080/1057563031000122121.

Abstract

A new flavonoid, dihydroglychalcone-A, was isolated from the leaves extract of Glycosmis chlorosperma in addition to two known sulphur-containing amides, dambullin and gerambullin. The structure of the new compound was assigned as 2'-hydroxy-4,6'-dimethoxy-3',4'-(2",2"-dimethylpyrano)dihydrochalcone. The extract of the leaves was also found to exhibit antimicrobial and cytotoxic activities.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chalcones
  • Flavonoids / chemistry*
  • Flavonoids / isolation & purification
  • Flavonoids / pharmacology
  • Humans
  • Leukemia-Lymphoma, Adult T-Cell / pathology
  • Microbial Sensitivity Tests
  • Plant Extracts / chemistry
  • Plant Leaves / chemistry
  • Rutaceae / chemistry*
  • Tumor Cells, Cultured

Substances

  • 2'-hydroxy-4,6'-dimethoxy-3',4'-(2'',2''-dimethylpyrano)dihydrochalcone
  • Chalcones
  • Flavonoids
  • Plant Extracts
  • dambulin
  • gerambulin