Bilateral renal artery occlusion in a patient with primary antiphospholipid antibody syndrome: thrombosis, vasculitis or both?

P R Ames; B Cianciaruso; V Bellizzi; M Balletta; E Lubrano; R Scarpa; V Brancaccio

Bilateral renal artery occlusion in a patient with primary antiphospholipid antibody syndrome: thrombosis, vasculitis or both?

J Rheumatol. 1992 Nov;19(11):1802-6.

Authors

P R Ames¹, B Cianciaruso, V Bellizzi, M Balletta, E Lubrano, R Scarpa, V Brancaccio

Affiliation

¹ Institute of Internal Medicine and Metabolic Diseases, 2nd Medical School, University of Naples, Italy.

PMID: 1491406

Abstract

A 43-year-old man presented with oliguria and hypertension. Renal arteriography showed bilateral renal artery occlusion. Circulating antiphospholipid antibodies were found together with a change in natural anticoagulant plasma levels. Immunofluorescence of examined vessels showed immune complex vasculitis. We discuss the pathogenetic mechanism leading to the development of this rare occlusive event.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Angiography
Antibodies, Antiphospholipid / analysis
Antiphospholipid Syndrome / complications*
Antiphospholipid Syndrome / diagnosis
Fluorescent Antibody Technique
Humans
Lupus Coagulation Inhibitor / analysis
Male
Renal Artery Obstruction / complications*
Renal Artery Obstruction / diagnosis
Thrombosis / complications*
Thrombosis / diagnosis
Vasculitis / complications*
Vasculitis / diagnosis

Substances

Antibodies, Antiphospholipid
Lupus Coagulation Inhibitor