The histological study of a painful cutaneous nodule located in the interscapular region, which had been present for 20 years in a 59-year old male patient has show typical features of dermal myxoma of the nerve sheaths. This was a lobulated myxomatous tumour with fusiform and dendritic cells plus a few epithelioid and multinucleate cells. Immunostaining was positive for the S100 protein and negative for factor XIIIa and EMA. These data suggest that this tumour was of schwannian origin.