Amyotrophic lateral sclerosis associated with the syndrome of inappropriate secretion of antidiuretic hormone

Intern Med. 1992 Aug;31(8):1023-5. doi: 10.2169/internalmedicine.31.1023.

Abstract

A 71-year-old female with amyotrophic lateral sclerosis (ALS) developed the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) during respiratory failure due to atrophy of the respiratory muscles. Serum sodium concentration fell to 116 mEq/l and then returned to the normal range after water restriction and respiratory care. This is considered to be the first case report of ALS associated with SIADH.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Amyotrophic Lateral Sclerosis / complications*
  • Amyotrophic Lateral Sclerosis / diagnosis
  • Blood Chemical Analysis
  • Electromyography
  • Female
  • Humans
  • Inappropriate ADH Syndrome / diagnosis
  • Inappropriate ADH Syndrome / etiology*
  • Respiratory Insufficiency / complications
  • Respiratory Insufficiency / etiology
  • Sodium / blood
  • Sodium / urine
  • Vasopressins / blood

Substances

  • Vasopressins
  • Sodium