Abstract
Taraxer-14-en-3beta-ol ( 1) was shown to be the active ingredient in the leaves of Sterculia foetida L. The alcohol 1, its acetate and ketone showed anti-inflammatory activity against TPA induced mouse ear oedema with inhibition ratios of 60.0, 58.57 and 40.57 at 0.5 mg/ear, respectively. The percentage inhibition of inflammation increased with dose for each compound.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
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Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Edema / chemically induced
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Edema / prevention & control*
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Male
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Mice
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Oleanolic Acid / administration & dosage
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Oleanolic Acid / analogs & derivatives*
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Oleanolic Acid / pharmacology*
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Oleanolic Acid / therapeutic use
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Phytotherapy*
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
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Plant Leaves
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Sterculia*
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Plant Extracts
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Oleanolic Acid
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taraxerol