Taraxer-14-en-3beta-ol, an anti-inflammatory compound from Sterculia foetida L

Planta Med. 2004 Jan;70(1):68-9. doi: 10.1055/s-2004-815459.

Abstract

Taraxer-14-en-3beta-ol ( 1) was shown to be the active ingredient in the leaves of Sterculia foetida L. The alcohol 1, its acetate and ketone showed anti-inflammatory activity against TPA induced mouse ear oedema with inhibition ratios of 60.0, 58.57 and 40.57 at 0.5 mg/ear, respectively. The percentage inhibition of inflammation increased with dose for each compound.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Edema / chemically induced
  • Edema / prevention & control*
  • Male
  • Mice
  • Oleanolic Acid / administration & dosage
  • Oleanolic Acid / analogs & derivatives*
  • Oleanolic Acid / pharmacology*
  • Oleanolic Acid / therapeutic use
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use
  • Plant Leaves
  • Sterculia*

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Plant Extracts
  • Oleanolic Acid
  • taraxerol