Objective: To explore the relationship between the change in neuron specific enolase (NSE) and brain malfunction in burned patients.
Methods: The serum samples of 11 burned patients with brain dysfunction were collected for the development of the serum level of neuron specific enolase with radioimmunoassay, and the correlation between condition of systemic inflammation and the levels of neuron specific enolase was assessed.
Results: The level of NSE in burn patients with cerebral malfunction was obviously higher than that in control, and the level was correlated with the systemic inflammation.
Conclusion: The change in the level of serum NSE could reflect the damage degree of central nervous system to some extent.