Analysis of Fz10 expression in mouse embryos

Dev Genes Evol. 2004 Mar;214(3):144-8. doi: 10.1007/s00427-004-0386-4. Epub 2004 Jan 31.

Abstract

Wnt signaling molecules regulate the development of multiple organs in vertebrate embryos. We have isolated cDNA clones for frizzled10 (Fz10), which encodes a putative Wnt receptor, to further characterize the mechanisms of Wnt signaling in mouse embryos. Interestingly, Fz10 is expressed in the same regions as Wnt7a in the neural tube, limb buds, and Müllerian duct.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Embryo, Mammalian / metabolism*
  • Extremities / embryology
  • Extremities / growth & development
  • Frizzled Receptors
  • Gene Expression Regulation, Developmental
  • Mice
  • Molecular Sequence Data
  • Receptors, Cell Surface / genetics*
  • Receptors, Cell Surface / metabolism
  • Receptors, G-Protein-Coupled
  • Sequence Homology, Amino Acid
  • Signal Transduction / physiology*

Substances

  • Frizzled Receptors
  • Fzd10 protein, mouse
  • Receptors, Cell Surface
  • Receptors, G-Protein-Coupled