Structural aspects of Golgi function

Cell Mol Life Sci. 2004 Jan;61(2):146-58. doi: 10.1007/s00018-003-3353-8.

Abstract

Since its discovery, the Golgi complex has attracted the attention of cell biologists because of its 'fashionable' morphology and central position within the secretory system of the cell. Here, we discuss how the three-dimensional architecture of the Golgi complex relates to its multiple functions in protein sorting and processing, and how an analysis of the morphology of the Golgi complex can help to provide an understanding of the mechanisms involved in transport through this unique organelle.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • COP-Coated Vesicles / physiology
  • Coat Protein Complex I / physiology
  • Golgi Apparatus / physiology*
  • Golgi Apparatus / ultrastructure*
  • Humans
  • Protein Transport / physiology

Substances

  • Coat Protein Complex I

Grants and funding