Abstract
The mutS gene of the methyl-directed mismatch repair system was sequenced in 10 parent and glycopeptide-intermediate Staphylococcus aureus strains. The mutS gene was intact in all strains studied. Hence, mutations in this gene had played no role in the development of vancomycin resistance in these strains.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Adenosine Triphosphatases / genetics*
-
Bacterial Proteins / genetics*
-
Base Pair Mismatch / genetics
-
Base Sequence
-
DNA Repair / genetics
-
DNA, Bacterial / biosynthesis
-
DNA, Bacterial / genetics
-
DNA-Binding Proteins / genetics*
-
Glycopeptides / genetics*
-
Methicillin Resistance / genetics
-
Molecular Sequence Data
-
MutS DNA Mismatch-Binding Protein
-
Mutation / genetics
-
Reverse Transcriptase Polymerase Chain Reaction
-
Staphylococcus aureus / drug effects
-
Staphylococcus aureus / genetics*
-
Staphylococcus aureus / growth & development
-
Vancomycin Resistance / genetics
Substances
-
Bacterial Proteins
-
DNA, Bacterial
-
DNA-Binding Proteins
-
Glycopeptides
-
Adenosine Triphosphatases
-
MutS DNA Mismatch-Binding Protein
Associated data
-
GENBANK/AY324086
-
GENBANK/AY324087
-
GENBANK/AY324088
-
GENBANK/AY324089
-
GENBANK/AY324090
-
GENBANK/AY324091
-
GENBANK/AY324092
-
GENBANK/AY324093
-
GENBANK/AY324094
-
GENBANK/AY324095
-
GENBANK/AY324096
-
GENBANK/AY324097