Purpose: To evaluate the visual function in different area at retinal posterior pole for the patients with cystoid macular edema (CME).
Methods: Multifocal ERG was tested using visual evoked response imaging system (VERIS) 4.0 for 24 patients (27 eyes) with CME and 25 normal control subjects whose ages matched patient's ages, the traces and 3D function maps of first order kernel response were recorded on 103 retinal locations of 26.6 degrees X22.1 degrees visual field.
Results: The latencies of N1 and P1 waves were remarkably prolonged at whole area and the 6 rings in the CME, there were statistically significant differences between the normal control group and CME (P < 0.01). Compared with normal control group, the average response densities of N1 wave at 1, 2, and 3 rings in the CME were seriously reduced (P < 0.01), but they in 4, 5 and 6 rings were not significantly changed (P > 0.05), the average response densities of P1 at whole area and the 6 rings were reduced (P < 0.05).
Conclusions: The mfERG is a promising tool to evaluate the visual function in different area at retinal posterior pole for the patients with CME. The response densities of N1 wave are better analysis index for CME.