Translocation of bioactive peptides across cell membranes by carbon nanotubes

Chem Commun (Camb). 2004 Jan 7:(1):16-7. doi: 10.1039/b311254c. Epub 2003 Nov 3.

Abstract

Functionalised carbon nanotubes are able to cross the cell membrane and to accumulate in the cytoplasm or reach the nucleus without being toxic for the cell up to 10 [micro sign]M.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 3T3 Cells
  • Animals
  • Cell Membrane / metabolism*
  • Flow Cytometry
  • Mice
  • Microscopy, Confocal
  • Microscopy, Fluorescence
  • Nanotubes, Carbon* / toxicity
  • Particle Size
  • Peptides / metabolism*
  • Protein Transport

Substances

  • Nanotubes, Carbon
  • Peptides