Progressive multifocal leukoencephalopathy in a patient with X-linked agammaglobulinemia

Scand J Infect Dis. 2003;35(11-12):909-10. doi: 10.1080/00365540310016673.

Abstract

To our knowledge, this is the first case report describing progressive multifocal leukoencephalopathy (PML) associated with X-linked agammaglobulinemia. The JC virus was confirmed at autopsy and PML was diagnosed. Humoral immunodeficiency with normal cellular immunity could be infected with JCV.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Agammaglobulinemia / complications*
  • Agammaglobulinemia / diagnosis
  • Agammaglobulinemia / genetics
  • Biopsy, Needle
  • Disease Progression
  • Fatal Outcome
  • Humans
  • Immunohistochemistry
  • JC Virus / isolation & purification*
  • Leukoencephalopathy, Progressive Multifocal / complications*
  • Leukoencephalopathy, Progressive Multifocal / diagnosis*
  • Male
  • Respiratory Insufficiency
  • Risk Assessment
  • Severity of Illness Index