Abstract
Identifying genomic locations of transcription-factor binding sites, particularly in higher eukaryotic genomes, has been an enormous challenge. Various experimental and computational approaches have been used to detect these sites; methods involving computational comparisons of related genomes have been particularly successful.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Base Sequence
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Binding Sites / genetics
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Chromosome Mapping / methods*
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Computational Biology / methods*
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Computational Biology / statistics & numerical data
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DNA, Fungal / genetics
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Humans
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Molecular Sequence Data
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Predictive Value of Tests
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Transcription Factors / genetics*
Substances
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DNA, Fungal
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Transcription Factors