Parallel fragment assembly strategy towards multiple-ether mimicry of anticancer annonaceous acetogenins

Angew Chem Int Ed Engl. 2004 Jan 3;43(3):329-34. doi: 10.1002/anie.200352681.

Authors

Sheng Jiang¹, Yan Li, Xiao-Guang Chen, Tai-Shan Hu, Yu-Lin Wu, Zhu-Jun Yao

Affiliation

¹ State Key Laboratory of Bioorganic, and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, 354 Fenglin Road, Shanghai 200032, China.

PMID: 14705089
DOI: 10.1002/anie.200352681

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Annonaceae / chemistry*
Antineoplastic Agents / chemical synthesis*
Antineoplastic Agents / chemistry
Antineoplastic Agents / pharmacology*
Biomimetic Materials / chemical synthesis
Biomimetic Materials / chemistry
Biomimetic Materials / pharmacology
Cell Line, Tumor
Doxorubicin / pharmacology
Ethers / chemical synthesis
Ethers / chemistry*
Ethers / pharmacology
Humans
Inhibitory Concentration 50
Lactones / chemical synthesis*
Lactones / chemistry*
Lactones / pharmacology
Stereoisomerism
Structure-Activity Relationship

Substances

Antineoplastic Agents
Ethers
Lactones
Doxorubicin