Lack of alterations on meiotic chromosomes and morphological characteristics of male germ cells in mice exposed to a 60 Hz and 2.0 mT magnetic field

Bioelectromagnetics. 2004 Jan;25(1):63-8. doi: 10.1002/bem.10184.

Abstract

The effect of in vivo exposure of mice to a 60 Hz sinusoidal magnetic field (MF) at 2.0 mT on male germ cells was studied. The cytological endpoints measured included meiotic chromosome aberrations in spermatocytes and sperm morphology. Three independent experiments were carried out: (a) animals exposed for 72 h, (b) 10 days/8 h daily, and (c) 72 h exposure to MF plus 5 mg/kg of Mitomycin-C. No statistically significant differences indicative of MF effects were observed between MF exposed and control animals. In addition, an opposite effect between MF exposure and Mitomycin-C treatment in terms of chromosomal aberrations and sperm morphology was observed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Size / radiation effects
  • Chromosome Aberrations*
  • Chromosomes / radiation effects*
  • Electricity*
  • Electromagnetic Fields*
  • Male
  • Meiosis / genetics*
  • Meiosis / radiation effects*
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred DBA
  • Radiation Dosage
  • Spermatozoa / pathology*
  • Spermatozoa / radiation effects*
  • Whole-Body Irradiation