Abstract
Testing of susceptibility to penicillin G by E-test and sequencing of an internal fragment of the penA gene were done for 43 meningococcal strains. Those strains for which the MIC was >/=0.094 micro g/ml showed mosaic alleles, so 0.094 micro g/ml is suggested as the penicillin G intermediate breakpoint when E-test is used.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alleles
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Ampicillin / pharmacology
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Anti-Bacterial Agents / pharmacology
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Genes, Bacterial / genetics*
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Neisseria meningitidis / drug effects
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Neisseria meningitidis / genetics*
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Penicillin G / pharmacology*
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Penicillins / pharmacology*
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Polymorphism, Genetic / genetics
Substances
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Anti-Bacterial Agents
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Penicillins
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Ampicillin
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Penicillin G
Associated data
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GENBANK/AF518612
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GENBANK/AF519575
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GENBANK/AF519576
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GENBANK/AF519577
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GENBANK/AF519579
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GENBANK/AF519581
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GENBANK/AF519582
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GENBANK/AF519584
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GENBANK/AF519585
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GENBANK/AF519586
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GENBANK/AF519587
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GENBANK/AF519588
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GENBANK/AF519589
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GENBANK/AF519590
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GENBANK/AF519591
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GENBANK/AF519596
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GENBANK/AF519603
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GENBANK/AF519607
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GENBANK/AF519609
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GENBANK/AF519616
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GENBANK/AF519617
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GENBANK/AY292990
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GENBANK/AY292991
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GENBANK/AY292992
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GENBANK/AY292993
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GENBANK/AY293001
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GENBANK/AY294547
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GENBANK/AY294548
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GENBANK/AY294549
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GENBANK/AY294550
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GENBANK/AY294551
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GENBANK/AY294552
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GENBANK/AY294553
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GENBANK/AY294554
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GENBANK/AY294555
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GENBANK/AY294556