Inhibition of Clotrimazole-resistant Candida albicans by plants used in Iranian folkloric medicine

Fitoterapia. 2004 Jan;75(1):74-6. doi: 10.1016/j.fitote.2003.08.012.

Abstract

In vitro anticandidal activity of methanol extracts of 42 plant species of 29 families used in Iranian folkloric medicine were evaluated at 20 mg/ml concentration against Clotrimazole-resistant Candida albicans. Nineteen plant species in 16 families showed anticandidal activities. The lowest MIC of 0.62 mg/ml belonged to Terminalia chebula and Thymus vulgaris.

MeSH terms

  • Antifungal Agents / administration & dosage
  • Antifungal Agents / pharmacology*
  • Antifungal Agents / therapeutic use
  • Candida albicans / drug effects*
  • Clotrimazole / pharmacology
  • Drug Resistance, Fungal*
  • Humans
  • Iran
  • Medicine, Traditional
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use
  • Plants, Medicinal*

Substances

  • Antifungal Agents
  • Plant Extracts
  • Clotrimazole