Evidence for a relationship between Group 1 mGluR hypofunction and increased cocaine and ethanol sensitivity in Homer2 null mutant mice

Ann N Y Acad Sci. 2003 Nov:1003:468-71. doi: 10.1196/annals.1300.055.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Carrier Proteins / genetics*
  • Carrier Proteins / physiology*
  • Central Nervous System Depressants / pharmacology*
  • Cocaine / pharmacology*
  • Conditioning, Operant / drug effects
  • Ethanol / pharmacology*
  • Excitatory Amino Acid Agonists / pharmacology
  • Homer Scaffolding Proteins
  • Methoxyhydroxyphenylglycol / analogs & derivatives*
  • Methoxyhydroxyphenylglycol / pharmacology
  • Mice
  • Mice, Knockout
  • Motor Activity / drug effects
  • Neuronal Plasticity / physiology
  • Neuropeptides / genetics*
  • Neuropeptides / physiology*
  • Receptors, Metabotropic Glutamate / genetics
  • Receptors, Metabotropic Glutamate / physiology*
  • Reward
  • Substance-Related Disorders / physiopathology

Substances

  • Carrier Proteins
  • Central Nervous System Depressants
  • Excitatory Amino Acid Agonists
  • Homer Scaffolding Proteins
  • Homer2 protein, mouse
  • Neuropeptides
  • Receptors, Metabotropic Glutamate
  • metabotropic glutamate receptor type 1
  • Ethanol
  • Methoxyhydroxyphenylglycol
  • Cocaine
  • 3,4-dihydroxyphenylglycol