Abstract
In view of biological activities of tiazofurin and azido or aminosugar nucleosides, novel azido- and amino-substituted tiazofurin derivatives (1 and 2) were efficiently synthesized starting from 1,2;5,6-di-O-isopropylidene-D-glucose.
MeSH terms
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Animals
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Antineoplastic Agents / chemical synthesis
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Antineoplastic Agents / pharmacology
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Enzyme Inhibitors / chemical synthesis*
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Enzyme Inhibitors / chemistry
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Enzyme Inhibitors / pharmacology
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Nucleosides / chemical synthesis
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Nucleosides / pharmacology
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Ribavirin / analogs & derivatives*
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Ribavirin / chemical synthesis*
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Ribavirin / chemistry
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Ribavirin / pharmacology
Substances
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Antineoplastic Agents
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Enzyme Inhibitors
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Nucleosides
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Ribavirin
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tiazofurin