The burden of amyloidosis on the gastrointestinal tract of an ankylosing spondylitis patient

Clin Rheumatol. 2003 Dec;22(6):440-2. doi: 10.1007/s10067-003-0755-9. Epub 2003 Oct 16.

Abstract

We present a 26-year-old man with edema, ascites and bloody diarrhea that later proved to be due to gastrointestinal and renal amyloidosis. Interestingly, he was also diagnosed as having ankylosing spondylitis,-possibly after a delay of 12 years. The obscure diagnosis and challenging treatment of secondary amyloidosis are further discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amyloidosis / complications
  • Amyloidosis / drug therapy
  • Amyloidosis / pathology*
  • Biopsy, Needle
  • Colchicine / administration & dosage
  • Colonoscopy
  • Disease Progression
  • Drug Therapy, Combination
  • Fatal Outcome
  • Gastrointestinal Diseases / complications
  • Gastrointestinal Diseases / drug therapy
  • Gastrointestinal Diseases / pathology*
  • Humans
  • Immunohistochemistry
  • Male
  • Melphalan / administration & dosage
  • Risk Assessment
  • Spondylitis, Ankylosing / complications*
  • Spondylitis, Ankylosing / diagnosis
  • Spondylitis, Ankylosing / therapy

Substances

  • Melphalan
  • Colchicine