Common-path interferometer for frequency-domain optical coherence tomography

Appl Opt. 2003 Dec 1;42(34):6953-8. doi: 10.1364/ao.42.006953.

Abstract

A Michelson-type spectral interferometer that uses a common beam path for the reference and the sample arms is described. This optical arrangement is more compact and stable than the more commonly used dual-arm interferometer and is well suited for frequency-domain optical coherence tomography of biological samples. With a 16-bit CCD camera, the instrument has sufficient dynamic range and resolution for imaging to depths of 2 mm in scattering biological materials. Images obtained with this spectral interferometer are presented, including cross-sectional images in a Xenopus laevis tadpole.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Abdomen / anatomy & histology*
  • Algorithms
  • Animals
  • Equipment Design
  • Equipment Failure Analysis
  • Feasibility Studies
  • Fourier Analysis
  • Image Interpretation, Computer-Assisted / methods*
  • Larva
  • Microscopy, Interference / instrumentation*
  • Microscopy, Interference / methods*
  • Scattering, Radiation
  • Tomography, Optical Coherence / instrumentation*
  • Tomography, Optical Coherence / methods*
  • Video Recording / instrumentation*
  • Video Recording / methods
  • Xenopus laevis