Prevalence of cholera toxin genes (ctxA and zot) among non-O1/O139 Vibrio cholerae strains from Newport Bay, California

Appl Environ Microbiol. 2003 Dec;69(12):7541-4. doi: 10.1128/AEM.69.12.7541-7544.2003.

Abstract

The examination of 137 non-O1/O139 Vibrio cholerae isolates from Newport Bay, California, indicated the presence of diverse genotypes and a temporal succession. Unexpectedly, the cholera toxin gene (ctxA) was found in 17% of the strains, of which one-third were also positive for the zot gene. This suggests that ctxA is prevalent in the region of nonepidemicity and is likely to have an environmental origin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • California
  • Cholera Toxin / genetics*
  • DNA Fingerprinting / methods
  • Endotoxins
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Vibrio cholerae / classification*
  • Vibrio cholerae / genetics
  • Vibrio cholerae / pathogenicity
  • Water Microbiology*

Substances

  • Endotoxins
  • zonula occludens toxin, Vibrio cholerae
  • Cholera Toxin

Associated data

  • GENBANK/AY376267
  • GENBANK/AY376268