Three-dimensional conformal radiation therapy (3D-CRT) for early-stage non-small-cell lung cancer

K E Rosenzweig; N Dladla; R Schindelheim; S E Sim; L E Braban; E S Venkataraman; S A Leibel

doi:10.3816/clc.2001.n.025

Three-dimensional conformal radiation therapy (3D-CRT) for early-stage non-small-cell lung cancer

Clin Lung Cancer. 2001 Nov;3(2):141-4. doi: 10.3816/clc.2001.n.025.

Authors

K E Rosenzweig¹, N Dladla, R Schindelheim, S E Sim, L E Braban, E S Venkataraman, S A Leibel

Affiliation

¹ Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. rosenzwk@mskcc.org

PMID: 14659030
DOI: 10.3816/clc.2001.n.025

Abstract

The standard treatment for early-stage non-small-cell lung cancer is surgical resection. However, many patients are inoperable due to medical comorbidities. Thirty-two medically inoperable patients with early-stage non-small-cell lung cancer were treated with 3-dimensional conformal radiation therapy between January 1991 and December 2000. The median dose was 70.2 Gy, and the median follow-up time in survivors was 30 months. The 2-year actuarial local control, overall survival, and cancer-specific survival rates were 43%, 54%, and 57%, respectively. The 5-year actuarial local control, overall survival, and cancer-specific survival rates were 43%, 33%, and 39%, respectively. This report suggests that local control is improved with high-dose conformal radiation therapy when compared to other institutions' retrospective experiences.