Abstract
Two new sulfur-containing compounds, trans-3-methylsulfonyl-2-propenol (1) and trans-3-methylsulfinyl-2-propenol (2) were isolated together with trans-3-methylthioacrylamide (3), entadamide A (4) and entadamide C (5) from the leaves of Clinacanthus siamensis. The structures were established on the basis of the spectroscopic data. The compounds were tested for antimalarial and antimycobacterial activity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acanthaceae*
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Animals
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Antitubercular Agents / pharmacology
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Mycobacterium tuberculosis / drug effects
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Mycobacterium tuberculosis / growth & development
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Plant Extracts / chemistry
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology
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Plant Leaves
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Plasmodium falciparum / drug effects
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Plasmodium falciparum / growth & development
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Sulfur Compounds / chemistry*
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Sulfur Compounds / isolation & purification
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Sulfur Compounds / pharmacology*
Substances
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Antitubercular Agents
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Plant Extracts
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Sulfur Compounds