Isolation and structures of new halogenated prostanoids from the Okinawan soft coral Clavularia viridis

J Nat Prod. 2003 Nov;66(11):1434-40. doi: 10.1021/np030181t.

Abstract

Fifteen new halogenated prostanoids 9-23 were isolated as minor constituents from the Okinawan soft coral Clavularia viridis. Compounds 9-11 were new members of iodovulone, and compounds 12-18 were 12-O-acetyliodovulones, 12-O-acetylbromovulones, and 12-O-acetylchlorovulones. Compounds 19-23 were 10,11-epoxy congeners of iodovulone, bromovulone, and chlorovulone. The structures of these compounds were determined on the basis of spectroscopic analysis and chemical conversion.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anthozoa / chemistry*
  • Hydrocarbons, Halogenated / chemistry*
  • Hydrocarbons, Halogenated / isolation & purification*
  • Japan
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Prostaglandins / chemistry*
  • Prostaglandins / isolation & purification*

Substances

  • Hydrocarbons, Halogenated
  • Prostaglandins