Abstract
Specific antibody opsonization significantly enhances the level of phagocytosis of Candida in the absence of complement. Furthermore, we have described a system using a recombinant human antibody single-chain variable fragment that allows a comparative study of phagocytosis of multiple Candida species opsonized via a common antigen.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Antibodies, Fungal / genetics
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Antibodies, Fungal / immunology
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Candida / classification*
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Candida / immunology*
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Humans
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Immunoglobulin Fragments / genetics
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Immunoglobulin Fragments / immunology*
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Immunoglobulin Variable Region
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Monocytes / immunology
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Neutrophils / immunology
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Opsonin Proteins / metabolism*
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Phagocytosis*
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Recombinant Proteins / immunology*
Substances
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Antibodies, Fungal
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Immunoglobulin Fragments
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Immunoglobulin Variable Region
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Opsonin Proteins
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Recombinant Proteins