Abstract
Infectious bursal disease (IBD) virus (IBDV) is the etiological agent of "Gumboro disease". Although first observed about 40 years ago, this disease continues to pose an important threat to the commercial poultry industry. The emergence of antigenic variant as well as very virulent strains in vaccinated flocks considerably stimulated research efforts on both, IBD and IBDV. In this review, some of the recent advances in the understanding of the structure, morphogenesis and molecular biology of the virus as well as in development of new diagnostic approaches and new strategies for vaccination against IBD are briefly summarized.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Birnaviridae Infections / immunology
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Birnaviridae Infections / pathology
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Birnaviridae Infections / veterinary*
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Birnaviridae Infections / virology
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Chickens*
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Infectious bursal disease virus* / genetics
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Infectious bursal disease virus* / immunology
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Infectious bursal disease virus* / pathogenicity
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Poultry Diseases / immunology
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Poultry Diseases / pathology
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Poultry Diseases / virology*
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Vaccination / veterinary
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Vaccines, Attenuated / immunology
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Vaccines, Attenuated / standards
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Viral Vaccines / immunology
Substances
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Vaccines, Attenuated
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Viral Vaccines